Every night I argue science live. Here is a year of it, charted.
I am a Ph.D. molecular biologist. At 9 PM Pacific I debate people who reject vaccines, evolution, climate science and germ theory, with the papers on screen. 219 of those streams are transcribed, so you can see what we actually argue about.
TonightLive nightly at 9 PM PTYouTube and TikTok, every night
Every night, what we argued about
Keyword mentions per stream, by topic
Figure 1A. Each column is one transcribed stream (219 streams, 659 hours, Sep 2025 to Sep 2026). Rows are the 8 topics that came up in the most streams. Each cell is shaded by how many times that topic's keywords appear in the stream transcript, on a log scale; cells under 3 mentions stay blank, matching the counting rule. "Shade within topic" scales each row to its own busiest night so quieter topics stay readable; "Across topics" uses one scale for all rows. The right margin shows streams where the topic's keywords came up 3 or more times. Rows are labeled directly, and the lower four swatches are hatched, so color is never the only cue. Click a topic to filter Figure 2.
Most asked on the show
Questions ranked by streams where they came up
All 8 questions. Pick a topic in Figure 1 to filter.
The receipt
Are mRNA vaccines safe?
In the 43,548-person Pfizer trial, side effects were short-term and mild to moderate: sore arm, fatigue, headache. Serious adverse events were low and similar in the vaccine and placebo groups.
Redrawn from published values.
Polack FP, et al. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N Engl J Med. 2020;383:2603-2615. doi:10.1056/NEJMoa2034577
Figure 2. (B) Bar length is the number of streams where the question came up (keyword match on transcripts), colored by topic; grey marks a topic outside the top 8. (C) The published result cited for the selected question. Charts are redrawn from published values; every citation links to its DOI or source.
Nightly streams with a transcript, Sep 2025 to Sep 2026. A topic counts for a stream when its keywords come up 3 or more times. Question counts are streams where the matching phrase came up at least once.
Topic hubs
The 8 topics that came up in the most streams. Each strip is the same 219-stream timeline from Figure 1.
Autism, mRNA, ingredients, schedules, mandates.
190 streamsAI and science125What AI can and cannot do in research, and the claims people make about it.
125 streamsCancer claims122Cures, causes, and what the trials actually show.
122 streamsEvolution113New information, fossils, "just a theory."
113 streamsClimate82IPCC reports, CO2, weather extremes, and the data behind them.
82 streamsGene editing64CRISPR, gene therapy, and what editing a genome really involves.
64 streamsGMOs and food56Genetically modified crops, glyphosate, and pesticides.
56 streamsCOVID origins54Market, lab, gain of function, and what the evidence can and cannot say.
54 streamsUpcoming
See all events- Sept 29, 2026
Big Homie CC vs 10, panelist
Digital Social Hour
Most popular videos
- 1
Kent Hovind Challenged a Real Scientist: Full Debate113,915 views - 2
Young-Earth Creationists vs. ACTUAL Scientific Evidence2,647 views - 3
Two Creationists Challenged Us on Human Evolution2,479 views - 4
A Climate Skeptic Asked for Evidence. We Went Through It.1,537 views - 5
I Confronted Alex Stein About Evolution. Here's What Happened.1,456 views - 6
8 Anti-Vaxxers Challenged a Real Scientist: Full Debate878 views
Figure 3. Views as of Sept 28, 2026. Source: YouTube view counts via vidIQ.
Games I made
All games
SimEcon
Pull the levers on taxes and programs and watch the impact on the US deficit, debt, and who pays. Every number is sourced to CBO, JCT, OMB, and Treasury.

SimEcon: San Diego
Run the City of San Diego's General Fund: police staffing, pensions, reserves, and the decisions history got wrong. Calibrated to the FY2026 Adopted Budget, IBA reports, and SDCERS valuations.

The Gap
A game about numbers you can't feel.

The Class Wargame
Click. Grind. Survive. Meanwhile, they don't have to. All dollar amounts are real. All data is sourced.
Search the transcripts
Find the exact moment a claim came up and jump to it on YouTube.
Think you can win?
Bring the claim you will defend and your best evidence. If it holds up to a first look, I will book you on the show.
Who you are debating
- Ph.D., Microbiology, UC Riverside
- Papers in Nature Nanotechnology and ACS Nano
- U.S. Patent US11186845B1
- NDSEG Fellow, Dept. of Defense
- Bench science at BASF and Cibus
Audience figures: Media kit, Sept 2026.