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Are mRNA vaccines safe?

In the 43,548-person Pfizer trial, side effects were short-term and mild to moderate: sore arm, fatigue, headache. Serious adverse events were low and similar in the vaccine and placebo groups.

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Receipt

Placebo162Vaccine8COVID-19 cases, 7+ days after dose 2

Redrawn from published values.

Polack FP, et al. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N Engl J Med. 2020;383:2603-2615. doi:10.1056/NEJMoa2034577